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Enquiries: NRC-IBD
Phone: 204-983-7692
Fax: 204-983-3154
Email: ibd.research@nrc-cnrc.gc.ca
435 Ellice Avenue
Winnipeg,
Manitoba,
R3B 1Y6
Canada
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Developing Diagnostic Tests for the Next Generation.
Disease diagnosis often begins with a tissue biopsy. It is only when specialized stains are applied that colours and contrast emerge and the secrets are revealed.
Colour and contrast in IR spectroscopic images form the basis for diagnosis without the application of any stains. Characteristic changes in tissue chemistry are reflected by characteristic changes in the infrared spectrum of that tissue. More than a complement to conventional pathology IR images offers a completely new window on disease incidence and progression.
Representative spectra of cervical epithelium.
Stained tissue section (left)
IR image (right).
The Spectroscopy Group at NRC-IBD is exploring the potential of mid-IR spectroscopy as a practical tool for the detection and diagnosis of cellular abnormalities, with applications including cervical cancer and leukemia. We have also characterized lung cancer tissue sections as a first step toward the development ofin vivodiagnostic and screening tools.
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