Common menu bar links
Introduction
Ultrasensitive detection and imaging methods are enabling technologies for the development of a new generation of medical diagnostics. Advances in this area require the molecular scale detection and imaging of individual biomolecules in the complex environment of a living cell. SIMS Biomolecular Sensing and Imaging Group develops and applies tools for molecular sensing and imaging and for understanding cellular processes. Current projects focus on the following areas: high resolution imaging of membrane organization, molecular sensing at chemically modified semiconductor surfaces and the development of chemical probes for functional genomics and proteomics and for the microfabrication of nanoscale devices. The BSI group maintains SIMS facilities for optical and scanning probe microscopy, surface characterization and cell culture.
Projects
Modification of Semiconductor Surfaces and Devices for Molecular Sensing
Nanoscale Imaging Methods for Validating a New Generation of FISH Probes
New Screening Technologies for Chemical Genomics
Quantitative Determination of Surface Markers on Chronic Lymphocytic Leukemia Cells
Using Chemical Biology to Understand the Molecular Mechanisms of Host-Pathogen Interactions
