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John Kelly
Phone: 613-998-5263
Fax: 613-952-9092
Email: John.Kelly@nrc-cnrc.gc.ca
Nuclear Magnetic Resonance Facility (NMR)
Dr. Jean Robert Brisson
Director, Immunobiology Program
National Research Council, Institute for Biological Sciences (NRC-IBS)
100 Sussex Drive
Sussex Room 3111
Ottawa, ON K1A 0R6
Phone (613) 990-3244
Fax (613) 941-1327
Jean-Robert.Brisson@nrc-cnrc.gc.ca
The NMR facility consists of three spectrometers (400, 500 and 600 MHz) that were last upgraded in 2002. Cold probe technology on the 600 MHz spectrometer permits the highest degree of sensitivity needed for glycan analysis and metabolomics studies. The 500 MHz spectrometer is equipped with unique High-Resolution Magic Angle capability for high throughput analysis of bacterial glycans in intact cells. The 400 MHz spectrometer is a multiple user (20) instrument for structural analysis of glycans and related chemical compounds. The 600 MHz spectrometer is part of the larger National Ultra-high Field NMR facility, an NRC-SIMS-IBS and University of Ottawa Partnered Facility.
High-field NMR is an essential tool for Institute research to meet the Biopharmaceutical and Bioproducts sectors.
The NMR Facility is managed and delivered within the Glycoprocessing and Glycoanalysis Program.
More about the facility:
• High resolution Varian NMR spectroscopy at 600, 500 and 400 MHz with solid state capabilities for the 400 MHz spectrometer.
• (1H, 13C, 15N, 2H) cryogenically cooled probe (cold-probe) for optimal sensitivity on the 4 channel 600 MHz spectrometer.
• (1H, 19F, X) MAS solid state capabilities on the 4 channel 400 MHz spectrometer.
• (1H, 31P, X), (1H, X) and broadband probes (X, 1H) for biological samples.
• Nano-probe for combinatorial chemistry.
• HR-MAS for cellular domains (bacterial cells, metabolites, cancer cells).
• Remote operation of spectrometers.
